New study connects asthma to mood disorders

A new study has found a connection between children suffering from asthma and developing a mood disorder.

According to a new study from the Taipei Veterans General Hospital in Taiwan, children who suffer from asthma are at an increased risk to develop some kind of mood disorder later in their lives.

The prospective study, conducted by researcher Ya-Mei Bai and colleagues, used information collected from insurance databases from 1998 to 2000 to identify all the children who have been diagnosed with asthma. A randomly selected control group for each patient was created, matched solely on age and gender. The patients had follow-up exams for their asthma diagnosis through the end of 2010.

What Ya-Mei Bai found was startling. She and her colleagues were able to definitively prove there is a connection between having asthma and developing mood issues, though it is not certain which disorder might occur. Children with asthma were twice as likely to be bipolar, and almost three times as likely to have any kind of depressive disorder. Roughly 2.8 percent of those kids with asthma were likely to be diagnosed as majorly depressed, a large contrast to the 1.1 percent of kids without asthma who have depression.

The study was also able to debunk a common myth about the connection between what is used to control asthma and bipolar disorder. Ya-Mei Bai and her associates found no significant relationship between usage of inhaled corticosteroids and being bipolar. The research suggests a dysfunctional regulation of the immune system is the most likely cause of asthma and emotional disorders. While the study shows there is a connection, further research needs to be done to find the root cause.

"Determining the underlying pathophysiology of the role of asthma and other allergic diseases in the development of mood disorders needs more investigation," Bai said in her work.

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